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022 _a09743626
040 _aMSU
_bEnglish
_cMSU
_erda
050 0 0 _aQD31 JOU
100 1 _aSheikhshoaie, Iran
_eauthor
245 1 0 _aSynthesis, characterization, X-ray crystal structure, electrochemical evaluation and anti-cancer studies of a mixed ligand Cu(II) complex of (E)-N′-((2-hydroxynaphthalen-1-yl)methylene)acetohydrazide /
_ccreated by Iran Sheikhshoaie, S. Yousef Ebrahimipour, Mahdieh Sheikhshoaie, Maryam Mohamadi, Mehdi Abbasnejad, Hadi Amiri Rudbari and Giuseppe Bruno
264 1 _aBangalore :
_bSpringer,
_c2015.
336 _2rdacontent
_atext
_btxt
337 _2rdamedia
_aunmediated
_bn
338 _2rdacarrier
_avolume
_bnc
440 _aJournal of chemical sciences
_vVolume 127, number 12,
520 3 _aA ternary mixed ligand Cu(II) complex, [Cu(L)(Phen)], was prepared from the reaction of (E)-N′-((2-hydroxynaphthalen-1-yl)methylene)acetohydrazide [HL], Cu(NO3)2.3H2O and 1,10-Phenanthroline in 1:1:1 molar ratio. This complex was fully characterized using spectroscopic and physicochemical methods. The structure of the complex was determined by single crystal X-ray diffraction. The Cu(II) center is coordinated by two oxygen and one nitrogen donors of L2− and nitrogen atoms of the heterocyclic group. Electrochemical studies of the Cu(II) complex showed shifts in the ligand peaks as well as the appearance of new peaks after complexation. The electrochemical behavior of the Cu(II) complex was also studied using cyclic voltammetry. According to biochemical investigation (MCF-7 cells viability), anticancer activity of [Cu(L)(Phen)] was higher than those of Cu(NO3)2.3H2O, HL and 1,10-Phenanthroline.
650 _aSchiff base
_vCu(II) complex
_xAnticancer activity
700 1 _aEbrahimipour, S. Yousef
_eco author
700 1 _aSheikhshoaie, Mahdieh
_eco author
700 1 _aMohamadi, Maryam
_eco author
700 1 _aAbbasnejad, Mehdi
_eco author
700 1 _aRudbari, Hadi Amiri
_eco author
700 1 _aBruno, Giuseppe
_eco author
856 _uhttps://doi.org/10.1007/s12039-015-0978-8
942 _2lcc
_cJA
999 _c169423
_d169423