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| 003 | ZW-GwMSU | ||
| 005 | 20250319085338.0 | ||
| 008 | 250319b |||||||| |||| 00| 0 eng d | ||
| 022 | _a0176-1617 | ||
| 040 |
_aMSU _bEnglish _cMSU _erda |
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| 050 | 0 | 0 | _aQK711..2 JOU |
| 100 | 1 |
_aLebedeva (Osipova), Maria A. _eauthor |
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| 245 | 1 | 0 |
_aInitiation of spontaneous tumors in radish (Raphanus sativus): Cellular, molecular and physiological events _ccreated by Maria A. Lebedeva (Osipova), Varvara E. Tvorogova, Alena P. Vinogradova, Maria S. Gancheva, Mahboobeh Azarakhsh, Elena L Ilina, Kirill N Demchenko, Irina E Dodueva and Lyudmila A. Lutova |
| 264 | 1 |
_aAmsterdam: _bElsevier GmbH, _c2015. |
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| 336 |
_2rdacontent _atext _btxt |
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| 337 |
_2rdamedia _aunmediated _bn |
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| 338 |
_2rdacarrier _avolume _bnc |
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| 440 |
_aJournal of Plant Physiology _vVolume 173 |
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| 520 | 3 | _aIn plant meristems, the balance of cell proliferation and differentiation is maintained by phytohormones, specifically auxin and cytokinin, as well as transcription factors. Changing of the cytokinin/auxin balance in plants may lead to developmental abnormalities, and in particular, to the formation of tumors. The examples of spontaneous tumor formation in plants include tumors formed on the roots of radish (Raphanus sativus) inbred lines. Previously, it was found that the cytokinin/auxin ratio is altered in radish tumors. In this study, a detailed histological analysis of spontaneous radish tumors was performed, revealing a possible mechanism of tumor formation, namely abnormal cambial activity. The analysis of cell proliferation patterns revealed meristematic foci in radish tumors. By using a fusion of an auxin-responsive promoter (DR5) and a reporter gene, the involvement of auxin in developmental processes in tumors was shown. In addition, the expression of the root meristem-specific WUSCHEL-related homeobox 5 (WOX5) gene was observed in cells adjacent to meristematic foci. Taken together, the results of the present study show that tumor tissues share some characteristics with root apical meristems, including the presence of auxin-response maxima in meristematic foci with adjacent cells expressing WOX5. | |
| 650 | _aAuxin | ||
| 650 | _aCambium | ||
| 650 | _aPlant tumors | ||
| 700 | 1 |
_aTvorogova, Varvara E. _eco-author |
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| 700 | 1 |
_aVinogradova, Alena P. _eco-author |
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| 700 | 1 |
_aGancheva, Maria S. _eco-author |
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| 700 | 1 |
_aAzarakhsh, Mahboobeh _eco-author |
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| 700 | 1 |
_aIlina, Elena L _eco-author |
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| 700 | 1 |
_aDemchenko, Kirill N _eco-author |
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| 700 | 1 |
_aDodueva, Irina E _eco-author |
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| 700 | 1 |
_aLutova, Lyudmila A. _eco-author |
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| 856 | _uhttps://doi.org/10.1016/j.jplph.2014.07.030 | ||
| 942 |
_2lcc _cJA |
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| 999 |
_c169371 _d169371 |
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