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| 005 | 20250318103017.0 | ||
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| 022 | _a09743626 | ||
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_aMSU _bEnglish _cMSU _erda |
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| 050 | 0 | 0 | _aQD31 JOU |
| 100 | 1 |
_aSaxena, Sachin _eauthor |
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| 245 | 1 | 0 |
_aVoltammetric determination of wedelolactone, an anti-HIV herbal drug, at boron-doped diamond electrode / _ccreated by Sachin Saxena, Ratnanjali Shrivastava and Soami P. Satsangee |
| 264 | 1 |
_aBangalore : _bSpringer, _c2015. |
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| 336 |
_2rdacontent _atext _btxt |
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| 337 |
_2rdamedia _aunmediated _bn |
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| 338 |
_2rdacarrier _avolume _bnc |
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| 440 |
_aJournal of chemical sciences _vVolume 127, number 5, |
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| 520 | 3 | _aBoron-doped diamond electrode has been utilized for the study of electrochemical behaviour of an anti-HIV herbal drug wedelolactone in Britton-Robinson buffer (pH-2.5) by square-wave and cyclic voltammetry techniques. The response characteristics of cyclic voltammetry and square wave voltammetry showed a remarkable increase in the anodic peak current and electrochemical impedance spectroscopy revealed a lowering in charge transfer resistance at the boron-doped diamond electrode as compared to the glassy carbon electrode that can be attributed to the higher sensitivity of boron-doped diamond sensor. Cyclic voltammetry at the boron-doped diamond surface revealed the oxidation of wedelolactone with two oxidation peaks (P1 and P2) with Ep1= 0.4V and Ep2=1.00 V with scan rate varying from 10 - 220 mV/s and exhibits diffusion-controlled process. Based on the electrochemical measurements, a probable oxidation mechanism has been deduced and the electrode dynamics parameters have been evaluated. The effect of concentration on the peak currents of wedelolactone was found to have a linear relationship within the concentration range of 50–700 ng/mL. The LOD and LOQ were found to be 43.87 and 132.93 ng/mL respectively. The applicability of the proposed method was further scrutinized by the successful determination of wedelolactone in real plant samples. | |
| 650 |
_aWedelolactone _vBoron-doped diamond electrode _xImpedance |
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| 700 | 1 |
_aShrivastava, Ratnanjali _eco author |
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| 700 | 1 |
_aSatsangee, Soami P. _eco author |
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| 856 | _uhttps://doi.org/10.1007/s12039-015-0853-7 | ||
| 942 |
_2lcc _cJA |
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_c169345 _d169345 |
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