| 000 | 02658nam a22003137a 4500 | ||
|---|---|---|---|
| 003 | ZW-GwMSU | ||
| 005 | 20250318070107.0 | ||
| 008 | 250318b |||||||| |||| 00| 0 eng d | ||
| 022 | _a0176-1617 | ||
| 040 |
_aMSU _bEnglish _cMSU _erda |
||
| 050 | _aQK711.2 JOU | ||
| 100 | 1 |
_aZulet, Amaia _eauthor |
|
| 245 | 1 | 0 |
_aFermentation and alternative oxidase contribute to the action of amino acid biosynthesis-inhibiting herbicides _ccreated by Amaia Zulet, Miriam Gil-Monreal, Ana Zabalza, Joost T. van Dongen and Mercedes Royuela |
| 264 | 1 |
_aAmsterdam: _bElsevier GmbH, _c2015. |
|
| 336 |
_2rdacontent _atext _btxt |
||
| 337 |
_2rdamedia _aunmediated _bn |
||
| 338 |
_2rdacarrier _avolume _bnc |
||
| 440 |
_aJournal of Plant Physiology _vVolume 175 |
||
| 520 | 3 | _aAcetolactate synthase inhibitors (ALS-inhibitors) and glyphosate (GLP) are two classes of herbicide that act by the specific inhibition of an enzyme in the biosynthetic pathway of branched-chain or aromatic amino acids, respectively. The physiological effects that are detected after application of these two classes of herbicides are not fully understood in relation to the primary biochemical target inhibition, although they have been well documented. Interestingly, the two herbicides’ toxicity includes some common physiological effects suggesting that they kill the treated plants by a similar pattern despite targeting different enzymes. The induction of aerobic ethanol fermentation and alternative oxidase (AOX) are two examples of these common effects. The objective of this work was to gain further insight into the role of fermentation and AOX induction in the toxic consequences of ALS-inhibitors and GLP. For this, Arabidopsis T-DNA knockout mutants of alcohol dehydrogenase (ADH) 1 and AOX1a were used. The results found in wild-type indicate that both GLP and ALS-inhibitors reduce ATP production by inducing fermentation and alternative respiration. The main physiological effects in the process of herbicide activity upon treated plants were accumulation of carbohydrates and total free amino acids. The effects of the herbicides on these parameters were less pronounced in mutants compared to wild-type plants. The role of fermentation and AOX regarding pyruvate availability is also discussed. | |
| 650 | _aAcetolactate synthase inhibitors | ||
| 650 | _aArabidopsis thaliana | ||
| 650 | _aEthanol fermentation | ||
| 700 | 1 |
_aGil-Monreal, Miriam _eco-author |
|
| 700 | 1 |
_aZabalza, Ana _eco-author |
|
| 700 | 1 |
_aVan Dongen, Joost T. _eco-author |
|
| 700 | 1 |
_aRoyuela, Mercedes _eco-author |
|
| 856 | _uhttps://doi.org/10.1016/j.jplph.2014.12.004 | ||
| 942 |
_2lcc _cJA |
||
| 999 |
_c169322 _d169322 |
||