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008 240508b |||||||| |||| 00| 0 eng d
020 _a9780123745132
040 _bEnglish
_cMSULIB
_erda
050 0 0 _aRA105.55 BUT
100 1 _aButler, John M.
_eauthor
245 1 0 _aAdvanced topics in forensic DNA typing :
_bmethodology /
_ccreated by John M. Butler
264 1 _bElsevier Academic Press,
_c2012
300 _axvii, 680 pages :
_billustrations ;
_c23 cm
336 _2rdacontent
_atext
337 _2rdamedia
_aunmediated
_bn
338 _2rdacarrier
_avolume
_bnc
504 _aIncludes index
505 _a1. Sample Collection, Storage, and Characterization 2. DNA Extraction Methods 3. DNA Quantitation 4. PCR Amplification: Capabilities and Cautions 5. Short Tandem Repeat (STR) Loci and Kits 6. Capillary Electrophoresis: Principles and Instrumentation 7. Quality Assurance and Validation 8. DNA Databases: Uses and Issues 9. Missing Persons and Disaster Victim Identification Efforts 10. Degraded DNA 11. Low-Level DNA Testing: Issues, Concerns, and Solutions 12. Single Nucleotide Polymorphisms and Applications 13. Y-Chromosome DNA Testing 14. Mitochondrial DNA Analysis 15. X-Chromosome Analysis 16. Non-Human DNA 17. New Technologies and Automation 18. Legal Aspects of DNA Testing and the Scientific Expert in Court Appendix 1 Reported Sizes and Sequences of STR Alleles Appendix 2 Familial DNA Searches: Potential, Pitfalls, and Privacy Concerns Appendix 3 List of Suppliers for DNA Instruments, Reagents, Services Appendix 4 Interviews Supporting Legal Aspects of DNA Testing. Sample collection, storage, and characterization DNA extraction methods DNA quantitation PCR amplification: capabilities and cautions Short tandem repeat (STR) loci and kits Capillary electrophoresis: principles and instrumentation Quality assurance and validation DNA databases: uses and issues Missing persons and disaster victim identification efforts Degraded DNA Low-level DNA testing: issues, concerns, and solutions Single nucleotide polymorphisms and applications Y-chromosome DNA testing Mitochondrial DNA analysis X-chromosome analysis Non-human DNA New technologies and automation Legal aspects of DNA testing and the scientific expert in court
520 _aIntended as a companion to the Fundamentals of Forensic DNA Typing volume published in 2009, Advanced Topics in Forensic DNA Typing: Methodology contains 18 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field and citation to more than 2800 articles and internet resources. The book builds upon the previous two editions of John Butler's internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. This book provides the most detailed information written to-date on DNA databases, low-level DNA, validation, and numerous other topics including a new chapter on legal aspects of DNA testing to prepare scientists for expert witness testimony. Over half of the content is new compared to previous editions. A forthcoming companion volume will cover interpretation issues. Contains the latest information - hot-topics and new technologies Well edited, attractively laid out, and makes productive use of its four-color format Author John Butler is ranked as the number one "high-impact author in legal medicine and forensic science, 2001 to 2011" by ScienceWatch.com
650 0 _aDNA Fingerprinting
650 0 _aDNA Fingerprinting methods
650 0 _aDNA physiology
942 _2lcc
_cB
999 _c165350
_d165350