000 03894nam a22003017a 4500
003 ZW-GwMSU
005 20201014103701.0
008 201014b ||||| |||| 00| 0 eng d
020 _a9780323530354
040 _bEnglish
_cMSU
_erda
041 _aeng
050 _aRL96
245 _aDermatopathology
_cedited by Thomas Brenn and Jason L. Hornick
260 _aPhiladelphia
_bElsevier
_c2017
300 _a511 pages
336 _2rdacontent
_atext
337 _2rdamedia
_aunmediated
_bn
338 _2rdacarrier
_avolume
_bnc
490 _aSurgical pathology clinics
_v10
505 _aPreface : Diagnostic challenges in dermatopathology / Thomas Brenn -- Spitz tumors of the skin / F.D. Menezes and W.J. Mooi -- Advances in the genetic characterization of cutaneous mesenchymal neoplasms : implications for tumor classification and novel diagnostic markers / Leigh A. Compton and Leona A. Doyle -- Atypical fibroxanthoma revisited / Thomas Mentzel, Luis Requena, and Thomas Brenn -- Cutaneous malignant peripheral nerve sheath tumor / Boštjan Luzar and Giovanni Falconieri -- Histopathology of spindle cell vascular tumors / Zlatko Marušić and Steven D. Billings -- Sebaceous neoplasms / Katharina Flux -- Update on malignant sweat gland tumors / Michiel P.J. van der Horst and Thomas Brenn -- Merkel cell carcinoma / Melissa Pulitzer -- Cutaneous lymphomas with cytotoxic phenotype / Adriana García-Herrera and Eduardo Calonje -- Epstein-Barr virus-associated lymphoproliferative disorders in the skin / John R. Goodlad -- Cutaneous pseudolymphoma / Christina Mitteldorf and Werner Kempf -- Histopathologic spectrum of connective tissue diseases commonly affecting the skin / Alvaro C. Laga, Allison Larson, and Scott R. Granter -- Immunofluorescence of autoimmune bullous diseases / Gilles F. Diercks, Hendri H. Pas, and Marcel F. Jonkman.
520 _aThe current review issue provides an update on selected and difficult topics across the clinical spectrum of dermatopathology, in the hope of providing the reader with an understanding of recent advances in the field and the diagnostic tools to tackle these challenges. The diagnosis of melanocytic tumors continues to represent one of the most challenging areas in surgical pathology, and Spitzoid tumors in particular remain a problematic and contentious topic. Significant progress has been made over the past years in our understanding of the underlying genetics and the behavior of these distinctive melanocytic tumors, which is discussed here in detail. Molecular advances have also had a particular impact on mesenchymal tumor pathology. The current body of knowledge as it relates to cutaneous mesenchymal tumors is reviewed with an emphasis on the development of novel markers. This is complemented by additional overviews on atypical fibroxanthoma, cutaneous malignant nerve sheath tumor, and vascular tumors with spindle cell morphology. Updates on skin adnexal tumor pathology include a review of the morphological spectrum of sebaceous neoplasms, a discussion of diagnostically challenging malignant sweat gland tumors, and Merkel cell carcinoma. The topic of cutaneous lymphoproliferative disorders is focused on the spectrum of tumors with a cytotoxic phenotype and Epstein-Barr virus-associated disorders. This is contrasted with an overview of reactive and inflammatory conditions mimicking lymphoproliferative disease, the so-called pseudolymphomas. Two articles dealing with inflammatory skin disorders conclude this review: an overview of the histologic spectrum of connective tissue disease in the skin and an outline of the significance of immunofluorescence in autoimmunone bullous disorders.
650 _aSkin
_xDiseases
650 _aSkin diseases
650 _aSkin
_xPathology
700 _aBrenn, Thomas
_eeditor
700 _aHornick, Jason L.
_eeditor
942 _2lcc
_cB
999 _c155382
_d155382