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Biomarkers in Alzheimer's disease Tapan Kumar Khan

By: Material type: TextTextLanguage: English Publisher: London San Diego Academic Press 2016Copyright date: ©2016Description: xi, 263 pages : illustrations (some coloured) ; 25 cmContent type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
ISBN:
  • 9780128048320
Subject(s): DDC classification:
  • 616.8/31075 23
LOC classification:
  • RC523 KHA
Contents:
Cover ; Title page; Copyright page; Contents; Foreword; Preface; Acknowledgments; Chapter 1 -- Introduction to Alzheimer's Disease Biomarkers ; 1.1 -- Historical Background; 1.2 -- Important Events in Alzheimer's Disease (AD) Research; 1.3 -- Some Facts About Alzheimer's Disease; 1.4 -- Common Features of Alzheimer's Disease; 1.5 -- Classification of Alzheimer's Disease; 1.6 -- Risk Factors for Alzheimer's Disease; 1.7 -- Definition of a Biomarker; 1.7.1 -- A. Categorization of Biomarkers According to Their Role. 1.7.2 -- B. Definition of Common Statistical Parameters to Quantify the Performance of Biomarkers1.8 -- Biomarkers of Alzheimer's Disease; 1.9 -- Future Focus: Detecting Preclinical Stages of Alzheimer's Disease; 1.10 -- Economic Impact of Alzheimer's Disease Biomarkers; 1.11 -- Conclusions; Bibliography; Chapter 2 -- Clinical Diagnosis of Alzheimer's Disease ; 2.1 -- Clinical Diagnosis of Alzheimer's Disease: Historical Perspective; 2.2 -- Neuropsychological Assessment Tests to Diagnose Alzheimer's Disease; 2.2.1 -- Mini-Mental State Examination; 2.2.2 -- Clock Drawing Test. 2.2.3 -- Alzheimer's Disease Assessment Scale2.2.4 -- Neuropsychological Test Battery; 2.2.4.1 -- Other neuropsychological tests; 2.2.5 -- Clinical Dementia Rating; 2.2.6 -- Global Deterioration Scale; 2.2.7 -- Dementia Severity Rating Scale; 2.3 -- Neuropathology at Brain Autopsy to Diagnose Alzheimer's Disease; 2.4 -- Accuracy of Clinical Diagnosis of Alzheimer's Disease; 2.5 -- Alzheimer's Disease-Related Neurological Conditions; 2.5.1 -- Preclinical Alzheimer's Disease; 2.5.2 -- Mild Cognitive Impairment; 2.5.3 -- Non-Alzheimer's Dementias; 2.5.3.1 -- Vascular dementia; 2.5.3.2 -- Lewy body dementia. 2.5.3.3 -- Frontotemporal dementia2.5.3.4 -- Creutzfeldt-Jacob disease; 2.5.3.5 -- Other non-AD dementias; 2.6 -- Challenges in Diagnosing Alzheimer's Disease; 2.6.1 -- Long Prodromal Stages; 2.6.2 -- Comorbidity With Non-Alzheimer's Disease Dementias; 2.6.3 -- Multiple Nongenetic and Genetic Factors; 2.6.4 -- Anomalous Alzheimer's Disease Neuropathology; 2.7 -- Comprehensive Alzheimer's Disease Diagnostic Framework; 2.8 -- Conclusions; Bibliography; Chapter 3 -- Neuroimaging Biomarkers in Alzheimer's Disease ; 3.1 -- Neuroimaging in Alzheimer's Disease; 3.1.1 -- Structural Neuroimaging. 3.1.2 -- Functional Neuroimaging3.1.3 -- Molecular Neuroimaging; 3.2 -- Common Neuroimaging Alzheimer's Disease Biomarkers and Modalities; 3.3 -- Magnetic Resonance Imaging; 3.3.1 -- Structural MRI; 3.3.2 -- Functional MRI; 3.3.3 -- Magnetic Resonance Spectroscopy; 3.3.4 -- Advanced Magnetic Resonance Based Neuroimaging Modalities; 3.3.4.1 -- Diffusion tensor imaging; 3.3.4.2 -- Arterial spin labeling MRI; 3.3.4.3 -- Task free fMRI; 3.4 -- Positron Emission Tomography; 3.4.1 -- Amyloid Imaging by PET; 3.4.2 -- Glucose Metabolism Measurement by PET; 3.4.3 -- Brain Inflammation Imaging by PET. 3.4.4 -- Tau Imaging by PET.
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Holdings
Item type Current library Call number Copy number Status Date due Barcode
Book Book Medical School Open Shelf RC523 KHA (Browse shelf(Opens below)) 147963 Available BK133888

Includes bibliographical references and index.

Cover ; Title page; Copyright page; Contents; Foreword; Preface; Acknowledgments; Chapter 1 --
Introduction to Alzheimer's Disease Biomarkers ; 1.1 --
Historical Background; 1.2 --
Important Events in Alzheimer's Disease (AD) Research; 1.3 --
Some Facts About Alzheimer's Disease; 1.4 --
Common Features of Alzheimer's Disease; 1.5 --
Classification of Alzheimer's Disease; 1.6 --
Risk Factors for Alzheimer's Disease; 1.7 --
Definition of a Biomarker; 1.7.1 --
A. Categorization of Biomarkers According to Their Role. 1.7.2 --
B. Definition of Common Statistical Parameters to Quantify the Performance of Biomarkers1.8 --
Biomarkers of Alzheimer's Disease; 1.9 --
Future Focus: Detecting Preclinical Stages of Alzheimer's Disease; 1.10 --
Economic Impact of Alzheimer's Disease Biomarkers; 1.11 --
Conclusions; Bibliography; Chapter 2 --
Clinical Diagnosis of Alzheimer's Disease ; 2.1 --
Clinical Diagnosis of Alzheimer's Disease: Historical Perspective; 2.2 --
Neuropsychological Assessment Tests to Diagnose Alzheimer's Disease; 2.2.1 --
Mini-Mental State Examination; 2.2.2 --
Clock Drawing Test. 2.2.3 --
Alzheimer's Disease Assessment Scale2.2.4 --
Neuropsychological Test Battery; 2.2.4.1 --
Other neuropsychological tests; 2.2.5 --
Clinical Dementia Rating; 2.2.6 --
Global Deterioration Scale; 2.2.7 --
Dementia Severity Rating Scale; 2.3 --
Neuropathology at Brain Autopsy to Diagnose Alzheimer's Disease; 2.4 --
Accuracy of Clinical Diagnosis of Alzheimer's Disease; 2.5 --
Alzheimer's Disease-Related Neurological Conditions; 2.5.1 --
Preclinical Alzheimer's Disease; 2.5.2 --
Mild Cognitive Impairment; 2.5.3 --
Non-Alzheimer's Dementias; 2.5.3.1 --
Vascular dementia; 2.5.3.2 --
Lewy body dementia. 2.5.3.3 --
Frontotemporal dementia2.5.3.4 --
Creutzfeldt-Jacob disease; 2.5.3.5 --
Other non-AD dementias; 2.6 --
Challenges in Diagnosing Alzheimer's Disease; 2.6.1 --
Long Prodromal Stages; 2.6.2 --
Comorbidity With Non-Alzheimer's Disease Dementias; 2.6.3 --
Multiple Nongenetic and Genetic Factors; 2.6.4 --
Anomalous Alzheimer's Disease Neuropathology; 2.7 --
Comprehensive Alzheimer's Disease Diagnostic Framework; 2.8 --
Conclusions; Bibliography; Chapter 3 --
Neuroimaging Biomarkers in Alzheimer's Disease ; 3.1 --
Neuroimaging in Alzheimer's Disease; 3.1.1 --
Structural Neuroimaging. 3.1.2 --
Functional Neuroimaging3.1.3 --
Molecular Neuroimaging; 3.2 --
Common Neuroimaging Alzheimer's Disease Biomarkers and Modalities; 3.3 --
Magnetic Resonance Imaging; 3.3.1 --
Structural MRI; 3.3.2 --
Functional MRI; 3.3.3 --
Magnetic Resonance Spectroscopy; 3.3.4 --
Advanced Magnetic Resonance Based Neuroimaging Modalities; 3.3.4.1 --
Diffusion tensor imaging; 3.3.4.2 --
Arterial spin labeling MRI; 3.3.4.3 --
Task free fMRI; 3.4 --
Positron Emission Tomography; 3.4.1 --
Amyloid Imaging by PET; 3.4.2 --
Glucose Metabolism Measurement by PET; 3.4.3 --
Brain Inflammation Imaging by PET. 3.4.4 --
Tau Imaging by PET.

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