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Biofluid mechanics : an introduction to fluid mechanics, macrocirculation, and microcirculation / created by David A. Rubenstein, Wei Yin, and Mary D. Frame, The Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY, USA.

By: Contributor(s): Material type: TextTextLanguage: English Series: Publication details: Amsterdam ; Boston : Elsevier/AP, Academic Press is an imprint of Elsevier, 2015.Edition: SecondDescription: 531 pages illustrations 25 cmContent type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
ISBN:
  • 9780128009444
Subject(s): LOC classification:
  • QP90.5 .R83 2015
NLM classification:
  • 2016 A-151
  • QU 105
Other classification:
  • mat
Contents:
Part I.Fluid mechanics basics; Chapter 1.Introduction, 1.1.Note to Students about the Textbook, 1.2.Biomedical Engineering, 3.Scope of Fluid Mechanics, 1.4.Scope of Biofluid Mechanics, 1.5.Dimensions and Units, 1.6.Salient Biofluid Mechanics ,Dimensionless Numbers, End of Chapter Summary, Reference Chapter 2 Fundamentals of fluid mechanics;2.1.Fluid Mechanics Introduction, 2.2.Fundamental Fluid Mechanics Equations, 2.3.Analysis Methods, 2.4.Fluid as a Continuum, 2.5.Elemental Stress and Pressure, 2.6.Kinematics: Velocity, Acceleration, Rotation, and Deformation, 2.7.Viscosity, 2.8.Fluid Motions, 2.9.Two-Phase Flows, 2.10.Changes in the Fundamental Relationships on the Microscale, 2.11.Fluid Structure Interaction, 2.12.Introduction to Turbulent Flows and the Relationship of Turbulence to Biological Systems, End of Chapter Summary, Homework Problems, References Chapter 3 Conservation Laws; 3.1.Fluid Statics Equations Note continued, 3.2.Buoyancy, 3.3.Conservation of Mass, 3.4.Conservation of Momentum, 3.5.Momentum Equation with Acceleration, 3.6.The First and Second Laws of Thermodynamics, 3.7.The Navier, Stokes Equations, 3.8.Bernoulli Equation, End of Chapter Summary, Homework Problems, Reference Part II.Macrocirculation; Chapter 4.The Heart, 4.1.Cardiac Physiology, 4.2.Cardiac Conduction System/Electrocardiogram, 4.3.The Cardiac Cycle, 4.4.Heart Motion, 4.5.Heart Valve Function, 4.6.Disease Conditions, 4.6.1.Coronary Artery Disease, 4.6.2.Myocardial Infarction, 4.6.3.Heart Valve Diseases, End of Chapter Summary, Homework Problems, References, 5.Blood Flow in Arteries and Veins, 5.1.Arterial System Physiology, 5.2.Venous System Physiology, 5.3.Blood Cells and Plasma, 5.4.Blood Rheology, 5.5.Pressure, Flow, and Resistance: Arterial System, 5.6.Pressure, Flow, and Resistance: Venous System, 5.7.Windkessel Model for Blood Flow Note continued: 5.8.Wave Propagation in Arterial Circulation, 5.9.Flow Separation at Bifurcations and at Walls, 5.10.Flow Through Tapering and Curved Channels, 5.11.Pulsatile Flow and Turbulence, 5.12.Disease Conditions, 5.12.1.Arteriosclerosis/Stroke/High Blood Pressure, 5.12.2.Platelet Activation/Thromboembolism, 5.12.3.Aneurysm, End of Chapter Summary, Homework Problems, References Part III.Microcirculation; Chapter 6.Microvascular Beds,6.1.Microcirculation Physiology, 6.2.Endothelial Cell and Smooth Muscle Cell Physiology, 6.3.Local Control of Blood Flow, 6.4.Pressure Distribution Throughout the Microvascular Beds, 6.5.Velocity Distribution Throughout the Microvascular Beds, 6.6.Interstitial Space Pressure and Velocity, 6.7.Hematocrit/Fahraeus, Lindquist Effect/Fahraeus Effect, 6.8.Plug Flow in Capillaries, 6.9.Characteristics of Two-Phase Flow, 6.10.Interactions Between Cells and the Vessel Wall, 6.11.Disease Conditions Note continued: 6.11.1.Shock/Tissue Necrosis, 6.11.2.Edema, End of Chapter Summary, Homework Problems, References, 7.Mass Transport and Heat Transfer in the Microcirculation, 7.1.Gas Diffusion, 7.2.Glucose Transport, 7.3.Vascular Permeability, 7.4.Energy Considerations, 7.5.Transport Through Porous Media, 7.6.Microcirculatory Heat Transfer, 7.7.Cell Transfer During Inflammation/White Blood Cell Rolling and Sticking, End of Chapter Summary, Homework Problems, References, 8.The Lymphatic System, 8.1.Lymphatic Physiology, 8.2.Lymph Formation, 8.3.Flow through the Lymphatic System, 8.4.Disease Conditions, 8.4.1.Cancer Metastasis via the Lymphatic System, 8.4.2.Lymphedema,End of Chapter Summary, Homework Problems, References, Part IV.Speciality circulations and otherbiological flows; Chapter 9.Flow in the Lungs, 9.1.Lung Physiology, 9.2.Elasticity of the Lung Blood Vessels and Alveoli Note continued: 9.3.Pressure-Volume Relationship for Air Flow in the Lungs, 9.4.Ventilation Perfusion Matching, 9.5.Oxygen/Carbon Dioxide Diffusion, 9.6.Oxygen/Carbon Dioxide Transport in the Blood, 9.7.Compressible Fluid Flow, 9.8.Disease Conditions, 9.8.1.Emphysema, 9.8.2.Asthma, 9.8.3.Tuberculosis, End of Chapter Summary, Homework Problems, References, 10.Intraocular Fluid Flow, 10.1.Eye Physiology, 10.2.Eye Blood Supply, Circulation, and Drainage, 10.3.Aqueous Humor Formation, 10.4.Aquaporins, 10.5.Flow of Aqueous Humor, 10.6.Intraocular Pressure, 10.7.Disease Conditions, 10.7.1.Glaucoma, 10.7.2.Cataracts, End of Chapter Summary, Homework Problems, References, 11.Lubrication of Joints and Transport in Bone, 11.1.Skeletal Physiology, 11.2.Bone Vascular Anatomy and Fluid Phases, 11.3.Formation of Synovial Fluid, 11.4.Synovial Fluid Flow 11.5.Mechanical Forces Within Joints Note continued:, 11.6.Transport of Molecules in Bone, 11.7.Disease Conditions, 11.7.1.Synovitis, 11.7.2.Bursitis/Tenosynovitis, End of Chapter Summary, Homework Problems, References, 12.Flow Through the Kidney, 12.1.Kidney Physiology, 12.2.Distribution of Blood in the Kidney, 12.3.Glomerular Filtration/Dynamics, 12.4.Tubule Reabsorption/Secretion, 12.5.Single Nephron Filtration Rate, 12.6.Peritubular Capillary Flow, 12.7.Sodium Balance and Transport of Important Molecules, 12.8.Autoregulation of Kidney Blood Flow, 12.9.Compartmental Analysis for Urine Formation, 12.10.Extracorporeal Flows: Dialysis, 12.11.Disease Conditions, 12.11.1.Renal Calculi, 12.11.2.Kidney Disease, End of Chapter Summary, Homework Problems, References, 13.Splanchnic Circulation: Liver and Spleen, 13.1.Liver and Spleen Physiology -- 13.2.Hepatic/Splenic Blood Flow, 13.3.Hepatic/Splenic Microcirculation Note continued: 13.4.Storage and Release of Blood in the Liver, 13.5.Active and Passive Components of the Splanchnic Circulation, 13.6.Innervation of the Spleen, 13.7.Disease Conditions, 13.7.1.Hepatitis, 13.7.2.Alcoholic and Fatty Liver Disease, 13.7.3.Splenomegaly, End of Chapter Summary, Homework Problems, References, V.Modeling and experimental techniques, 14.In Silico Biofluid Mechanics, 14.1.Computational Fluid Dynamics, 14.2.Fluid Structure Interaction Modeling, 14.3.Buckingham Pi Theorem and Dynamic Similarity, 14.4.Current State of the Art for Biofluid Mechanics in Silico Research, 14.5.Future Directions of Biofluid Mechanics in Silico Research, End of Chapter Summary -- Homework Problems, References, 15.In Vitro Biofluid Mechanics, 15.1.Particle Imaging Velocimetry, 15.2.Laser Doppler, Velocimetry, 15.3.Flow Chambers: Parallel Plate/Cone-and-Plate Viscometry Note continued: 15.4.Current State of the Art for Biofluid Mechanics in Vitro Research, 15.5.Future Directions of Biofluid Mechanics In Vitro Research, End of Chapter Summary, Homework Problems, References, 16.In Vivo Biofluid Mechanics, 16.1.Live Animal Preparations, 16.2.Doppler Ultrasound, 16.3.Phase Contrast Magnetic Resonance Imaging, 16.4.Review of Other Techniques, 16.5.Current State of the Art for Biofluid Mechanics In Vivo Research, 16.6.Future Directions of Biofluid Mechanics In Vivo Research, End of Chapter Summary, Homework Problems, References.
Summary: Biofluid Mechanics: An Introduction to Fluid Mechanics, Macrocirculation, and Microcirculation shows how fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement, renal transport among other specialty circulations. This new second edition increases the breadth and depth of the original by expanding chapters to cover additional biofluid mechanics principles, disease criteria, and medical management of disease, with supporting discussions of the relevance and importance of current research. Calculations related both to the disease and the material covered in the chapter are also now provided.
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Book Book Main Library Core Collection QH513 RUB (Browse shelf(Opens below)) 150052 Available BK135520

Includes bibliographical references and index.

Part I.Fluid mechanics basics; Chapter 1.Introduction, 1.1.Note to Students about the Textbook, 1.2.Biomedical Engineering, 3.Scope of Fluid Mechanics, 1.4.Scope of Biofluid Mechanics, 1.5.Dimensions and Units, 1.6.Salient Biofluid Mechanics ,Dimensionless Numbers, End of Chapter Summary, Reference Chapter 2 Fundamentals of fluid mechanics;2.1.Fluid Mechanics Introduction, 2.2.Fundamental Fluid Mechanics Equations, 2.3.Analysis Methods, 2.4.Fluid as a Continuum, 2.5.Elemental Stress and Pressure, 2.6.Kinematics: Velocity, Acceleration, Rotation, and Deformation, 2.7.Viscosity, 2.8.Fluid Motions, 2.9.Two-Phase Flows, 2.10.Changes in the Fundamental Relationships on the Microscale, 2.11.Fluid Structure Interaction, 2.12.Introduction to Turbulent Flows and the Relationship of Turbulence to Biological Systems, End of Chapter Summary, Homework Problems, References Chapter 3 Conservation Laws; 3.1.Fluid Statics Equations Note continued, 3.2.Buoyancy, 3.3.Conservation of Mass, 3.4.Conservation of Momentum, 3.5.Momentum Equation with Acceleration, 3.6.The First and Second Laws of Thermodynamics, 3.7.The Navier, Stokes Equations, 3.8.Bernoulli Equation, End of Chapter Summary, Homework Problems, Reference Part II.Macrocirculation; Chapter 4.The Heart, 4.1.Cardiac Physiology, 4.2.Cardiac Conduction System/Electrocardiogram, 4.3.The Cardiac Cycle, 4.4.Heart Motion, 4.5.Heart Valve Function, 4.6.Disease Conditions, 4.6.1.Coronary Artery Disease, 4.6.2.Myocardial Infarction, 4.6.3.Heart Valve Diseases, End of Chapter Summary, Homework Problems, References, 5.Blood Flow in Arteries and Veins, 5.1.Arterial System Physiology, 5.2.Venous System Physiology, 5.3.Blood Cells and Plasma, 5.4.Blood Rheology, 5.5.Pressure, Flow, and Resistance: Arterial System, 5.6.Pressure, Flow, and Resistance: Venous System, 5.7.Windkessel Model for Blood Flow Note continued: 5.8.Wave Propagation in Arterial Circulation, 5.9.Flow Separation at Bifurcations and at Walls, 5.10.Flow Through Tapering and Curved Channels, 5.11.Pulsatile Flow and Turbulence, 5.12.Disease Conditions, 5.12.1.Arteriosclerosis/Stroke/High Blood Pressure, 5.12.2.Platelet Activation/Thromboembolism, 5.12.3.Aneurysm, End of Chapter Summary, Homework Problems, References Part III.Microcirculation; Chapter 6.Microvascular Beds,6.1.Microcirculation Physiology, 6.2.Endothelial Cell and Smooth Muscle Cell Physiology, 6.3.Local Control of Blood Flow, 6.4.Pressure Distribution Throughout the Microvascular Beds, 6.5.Velocity Distribution Throughout the Microvascular Beds, 6.6.Interstitial Space Pressure and Velocity, 6.7.Hematocrit/Fahraeus, Lindquist Effect/Fahraeus Effect, 6.8.Plug Flow in Capillaries, 6.9.Characteristics of Two-Phase Flow, 6.10.Interactions Between Cells and the Vessel Wall, 6.11.Disease Conditions Note continued: 6.11.1.Shock/Tissue Necrosis, 6.11.2.Edema, End of Chapter Summary, Homework Problems, References, 7.Mass Transport and Heat Transfer in the Microcirculation, 7.1.Gas Diffusion, 7.2.Glucose Transport, 7.3.Vascular Permeability, 7.4.Energy Considerations, 7.5.Transport Through Porous Media, 7.6.Microcirculatory Heat Transfer, 7.7.Cell Transfer During Inflammation/White Blood Cell Rolling and Sticking, End of Chapter Summary, Homework Problems, References, 8.The Lymphatic System, 8.1.Lymphatic Physiology, 8.2.Lymph Formation, 8.3.Flow through the Lymphatic System, 8.4.Disease Conditions, 8.4.1.Cancer Metastasis via the Lymphatic System, 8.4.2.Lymphedema,End of Chapter Summary, Homework Problems, References, Part IV.Speciality circulations and otherbiological flows; Chapter 9.Flow in the Lungs, 9.1.Lung Physiology, 9.2.Elasticity of the Lung Blood Vessels and Alveoli Note continued: 9.3.Pressure-Volume Relationship for Air Flow in the Lungs, 9.4.Ventilation Perfusion Matching, 9.5.Oxygen/Carbon Dioxide Diffusion, 9.6.Oxygen/Carbon Dioxide Transport in the Blood, 9.7.Compressible Fluid Flow, 9.8.Disease Conditions, 9.8.1.Emphysema, 9.8.2.Asthma, 9.8.3.Tuberculosis, End of Chapter Summary, Homework Problems, References, 10.Intraocular Fluid Flow, 10.1.Eye Physiology, 10.2.Eye Blood Supply, Circulation, and Drainage, 10.3.Aqueous Humor Formation, 10.4.Aquaporins, 10.5.Flow of Aqueous Humor, 10.6.Intraocular Pressure, 10.7.Disease Conditions, 10.7.1.Glaucoma, 10.7.2.Cataracts, End of Chapter Summary, Homework Problems, References, 11.Lubrication of Joints and Transport in Bone, 11.1.Skeletal Physiology, 11.2.Bone Vascular Anatomy and Fluid Phases, 11.3.Formation of Synovial Fluid, 11.4.Synovial Fluid Flow
11.5.Mechanical Forces Within Joints Note continued:, 11.6.Transport of Molecules in Bone, 11.7.Disease Conditions, 11.7.1.Synovitis, 11.7.2.Bursitis/Tenosynovitis, End of Chapter Summary, Homework Problems, References, 12.Flow Through the Kidney, 12.1.Kidney Physiology, 12.2.Distribution of Blood in the Kidney, 12.3.Glomerular Filtration/Dynamics, 12.4.Tubule Reabsorption/Secretion, 12.5.Single Nephron Filtration Rate, 12.6.Peritubular Capillary Flow, 12.7.Sodium Balance and Transport of Important Molecules, 12.8.Autoregulation of Kidney Blood Flow, 12.9.Compartmental Analysis for Urine Formation, 12.10.Extracorporeal Flows: Dialysis, 12.11.Disease Conditions, 12.11.1.Renal Calculi, 12.11.2.Kidney Disease, End of Chapter Summary, Homework Problems, References, 13.Splanchnic Circulation: Liver and Spleen, 13.1.Liver and Spleen Physiology --
13.2.Hepatic/Splenic Blood Flow, 13.3.Hepatic/Splenic Microcirculation Note continued: 13.4.Storage and Release of Blood in the Liver, 13.5.Active and Passive Components of the Splanchnic Circulation, 13.6.Innervation of the Spleen, 13.7.Disease Conditions,
13.7.1.Hepatitis, 13.7.2.Alcoholic and Fatty Liver Disease, 13.7.3.Splenomegaly, End of Chapter Summary, Homework Problems, References, V.Modeling and experimental techniques, 14.In Silico Biofluid Mechanics, 14.1.Computational Fluid Dynamics, 14.2.Fluid Structure Interaction Modeling, 14.3.Buckingham Pi Theorem and Dynamic Similarity, 14.4.Current State of the Art for Biofluid Mechanics in Silico Research, 14.5.Future Directions of Biofluid Mechanics in Silico Research, End of Chapter Summary --
Homework Problems, References, 15.In Vitro Biofluid Mechanics, 15.1.Particle Imaging Velocimetry, 15.2.Laser Doppler, Velocimetry, 15.3.Flow Chambers: Parallel Plate/Cone-and-Plate Viscometry Note continued: 15.4.Current State of the Art for Biofluid Mechanics in Vitro Research, 15.5.Future Directions of Biofluid Mechanics In Vitro Research, End of Chapter Summary, Homework Problems, References, 16.In Vivo Biofluid Mechanics, 16.1.Live Animal Preparations, 16.2.Doppler Ultrasound, 16.3.Phase Contrast Magnetic Resonance Imaging, 16.4.Review of Other Techniques, 16.5.Current State of the Art for Biofluid Mechanics In Vivo Research, 16.6.Future Directions of Biofluid Mechanics In Vivo Research, End of Chapter Summary, Homework Problems, References.

Biofluid Mechanics: An Introduction to Fluid Mechanics, Macrocirculation, and Microcirculation shows how fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement, renal transport among other specialty circulations. This new second edition increases the breadth and depth of the original by expanding chapters to cover additional biofluid mechanics principles, disease criteria, and medical management of disease, with supporting discussions of the relevance and importance of current research. Calculations related both to the disease and the material covered in the chapter are also now provided.

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