TY - BOOK AU - Sheikhshoaie,Iran AU - Ebrahimipour,S.Yousef AU - Sheikhshoaie,Mahdieh AU - Mohamadi,Maryam AU - Abbasnejad,Mehdi AU - Rudbari,Hadi Amiri AU - Bruno,Giuseppe TI - Synthesis, characterization, X-ray crystal structure, electrochemical evaluation and anti-cancer studies of a mixed ligand Cu(II) complex of (E)-N′-((2-hydroxynaphthalen-1-yl)methylene)acetohydrazide SN - 09743626 AV - QD31 JOU PY - 2015/// CY - Bangalore PB - Springer KW - Schiff base KW - Cu(II) complex KW - Anticancer activity N2 - A ternary mixed ligand Cu(II) complex, [Cu(L)(Phen)], was prepared from the reaction of (E)-N′-((2-hydroxynaphthalen-1-yl)methylene)acetohydrazide [HL], Cu(NO3)2.3H2O and 1,10-Phenanthroline in 1:1:1 molar ratio. This complex was fully characterized using spectroscopic and physicochemical methods. The structure of the complex was determined by single crystal X-ray diffraction. The Cu(II) center is coordinated by two oxygen and one nitrogen donors of L2− and nitrogen atoms of the heterocyclic group. Electrochemical studies of the Cu(II) complex showed shifts in the ligand peaks as well as the appearance of new peaks after complexation. The electrochemical behavior of the Cu(II) complex was also studied using cyclic voltammetry. According to biochemical investigation (MCF-7 cells viability), anticancer activity of [Cu(L)(Phen)] was higher than those of Cu(NO3)2.3H2O, HL and 1,10-Phenanthroline UR - https://doi.org/10.1007/s12039-015-0978-8 ER -