TY - BOOK AU - Boulis,Nicholas AU - O'Connor,Deirdre M. AU - Donsante,Anthony TI - Molecular and cellular therapies for motor neuron diseases SN - 9780128022573 AV - RC349.8 MOL PY - 2017/// CY - London PB - Elsevier, Academic Press KW - Motor neurons KW - Diseases KW - Treatment KW - Neuromuscular diseases KW - Motor Neuron Disease KW - Therapy KW - Molecular Targeted Therapy KW - Methods KW - Cell- and Tissue-Based Therapy N1 - Includes bibliographical references and index; 1. Molecular and extracellular cues in motor neuron specification and differentiation / R.L. Swetenburg, S.L. Stice and L. Karumbaiah -- 2. Natural history of amyotrophic lateral sclerosis / M.J. Magnussen and J.D. Glass -- 3. Genetics of amyotrophic lateral sclerosis / K.P. Kenna, J.E. Landers and N. Ticozzi -- 4. Molecular mechanisms of amytrophic lateral sclerosis / M. Collins and R. Bowser -- 5. An introduction to natural history, genetic mapping, and clinical spectrum of spinal muscular atrophy / A. McDonough, L. Urquia and N. Boulis -- 6. Genetics of spinal muscular atrophy / A.H.M. Burghes and V.L. McGovern -- 7. Introduction to gene and stem-cell therapy / D.M. O'Connor -- 8. Gene therapy for amytrophic lateral sclerosis / A. Dosante -- 9. Stem cell therapy for amytrophic lateral sclerosis / K.S. Chen and E.L. Feldman -- 10. Gene therapy for spinal muscular atrophy / M.R. Miller, E.Y. Osman and C.L. Lorson -- 11. Cellular therapy for spinal muscular atrophy / I. Faravelli and S. Corti -- 12. Clinical trials to date / B.J. Mader and N. Boulis ER -