Clinical biochemistry / Peter Rae, Mike Crane, Rebecca Pattenden lecture notes

Preceded by Clinical biochemistry: lecture notes. 9th edition. / Geoffrey Beckett. 2013.

This book includes a companion website at www.lecturenotes.com/clinicalbiochemistry featuring self-assessments and downloadable summary slides for revision.

Also available as an e-book

Includes bibliographical references and index.

Requesting and interpreting tests -- Disturbances of water, sodium and potassium balance -- Acid' base balance and oxygen transport -- Renal disease -- Disorders of calcium, phosphate and magnesium metabolism -- Diabetes mellitus and hypoglycaemia -- Disorders of the hypothalamus and pituitary -- Abnormalities of thyroid function -- Disorders of the adrenal cortex and medulla -- Investigation of gonadal function infertility, menstrual irregularities and hirsutism -- Pregnancy and antenatal screening -- Cardiovascular disorders -- Liver disease -- Gastrointestinal tract disease -- Nutrition -- Trauma, inflammation and immunity -- Malignancy and tumour markers -- Disorders of iron and porphyrin metabolism -- Uric acid, gout and purine metabolism -- Central nervous system and cerebrospinal fluid -- Therapeutic drug monitoring and chemical toxicology -- Clinical biochemistry in paediatrics and the elderly.

Clinical biochemistry lecture notes presents the fundamental science behind common biochemical investigations used in clinical practice. Taking a system-based approach, it explores the underlying physiological rationale for tests, with each test explained within the context of disruption by disease. It also explores the value and limitations of biochemical investigations, while helping readers to quickly develop the knowledge and skills required to select the appropriate investigations for diagnosis and management, and correctly interpret test results. Case studies place the information within a clinical context to further assist readers in the development of test-selection and interpretation skills.