Introduction to bioinformatics : a theoretical and practical approach / edited by Stephen A. Krawetz and David D. Womble

Includes index

Part I. Biochemistry, cell, and molecular biology: A. The Cell. Nucleic acids and proteins: modern linguistics for the genomics and bioinformatics era / Bradley C. Hyman Structure and function of cell organelles / Jon Holy Cell signaling / Daniel A. Rappolee B. Transcription and translatio. DNA replication, repair, and recombination / Linda B. Bloom Transcription, RNA processing, and translation / Thomas P. Yang and Thomas W. O'Brien Part II. Molecular genetics: A. Genomics. Epigenetic mechanisms regulating gene expression / John R. McCarrey Gene families and evolution / Ben F. Koop Repetitive DNA: detection, annotation, and analysis / Jerzy Jurka Molecular genetics of disease and the human genome project / Paromita Deb-Rinker and Stephen W. Scherer B. Clinical human genetics. Heredity / C.A. Rupar The clinical genetics databases / Peter J. Bridge Poulation genetics / Jill S. Barnholtz-Sloan. The UNIX operating system: A. Basics and installation. Introduction to UNIX for biologists / David D. Womble Installation of the sun solaris (TM) operating environment / Bryon Campbell Sun system administration / Bryon Campbell B. Managing bioinformatics tools. Installing bioinformatics software in a server-based computing environment / Brian Fristensky Management of a server-based bioinformatics resource / Brian Fristensky C. Command line sequence analysis. GCG file management / Sittichoke Saisanit Part IV. Computer applications: A. Management and alalysis of DNA sequencing projects and sequences. Managing sequencing projects in the GAP4 environment / Rodger Staden, David P. Judge, and James K. Bonfield OLIGO primer analysis software / John D. Offerman and Wojciech Rychlik Statistical modeling of DNA seuences and patterns / Gautam B. Singh Statistical mining of the matrix attachment regions in geonomic sequences / Gautam B. Singh Analyzing sequences using the Staden package and EMBOSS / Rodger Staden, David P. Judge, and James K. Bonfield B. The genome database: analysis and similarity searching. Ensembl: an open-source software tool for large-scale genome analysis / James W. Stalker and Anthony V. Cox The PIR for functional genomics and proteomics / Cathy H. Wu. Sequence similarity and database searching / David S. Wishart GCG database searching / David J. Heard C. Identifying functional and structural sequence elements. Pattern discovery: methods and software / Brona Brejova, Tomas Vinar, and Ming Li The role of transcription factor binding sites in promoters and their In Silico detection / Thomas Werner An introduction to multiple sequence alignment and analysis / Steven M. Thompson 3D molecular visualization with protein explorer / Eric Martz Multiple sequence alignment and analysis: the Seqlab interface: a practical guide / Steven M. Thompson D. Analysis of gene expression: microarrays and other tools. Overview of the tools for microarray analysis: transcription profiling, DNA chips, and differential display / Jeffrey A. Kramer Microarays: tools for gene expression analysis / Sorin Draghici Knowledge discovery from the human transcriptome / Kousaku Okubo and Teruyoshi Hishiki.l

CD-ROM contains: chapter illustrations -- full and trial versions of programs