Pathologic Basis of Veterinary Disease / edited by James F. Zachary,DVM, PhD, DACVP Professor Emeritus of Veterinary Pathology Department of Pathology College of Veterinary Medicine University of Illinois Urbana, Illinois

Includes index

Front Cover; Inside Front Cover; Pathologic Basis of Veterinary Disease; Copyright Page; Contributors; Preface; New to This Edition; Acknowledgments; 5th Edition; 4th Edition; 3rd Edition (as Thompson's Special Veterinary Pathology); ExpertConsult Website; About the Cover; In Conclusion; In Appreciation: Dr. M. Donald McGavin; Table Of Contents; I General Pathology; 1 Mechanisms and Morphology of Cellular Injury, Adaptation, and Death; Key Readings Index; E-Glossary 1-1 Glossary of Abbreviations and Terms; Basic Terminology; The Normal Cell. Components of Normal Cells and Their VulnerabilitiesCell Membranes (Cytocavitary System); Second Messenger Systems.; Cytosol versus Cytoplasm; Nucleus; Nucleolus.; Rough Endoplasmic Reticulum; Ribosomes.; Golgi Complex; Smooth Endoplasmic Reticulum; Mitochondria; Oxidative Phosphorylation; Vaults; Lysosomes and Peroxisomes; The Cytoskeleton: Microfilaments, Intermediate Filaments, and Microtubules; Cellular Inclusions; Intercellular Junctions and the Extracellular Matrix; Causes of Cell Injury; Oxygen Deficiency; Physical Agents; Infectious Microbes; Nutritional Imbalances. Genetic DerangementWorkload Imbalance; Chemicals, Drugs, and Toxins; Immunologic Dysfunction; Aging; Reversible Cell Injury; Acute Cell Swelling; Mechanisms of Acute Cell Swelling; Acute Cell Swelling Resulting from Hypoxic Injury; Acute Cell Swelling Resulting from Specific Types of Cell Membrane Injury; Carbon Tetrachloride and Cell Membrane Injury; Molecules of the Immune System and Cell Membrane Injury.; Morphologic Changes: Their Detection and Evaluation; Morphology of Acute Cell Swelling; Gross Appearance.; Microscopic Appearance.; Ultrastructural Appearance. Significance and Fate of Acute Cell SwellingIrreversible Cell Injury and Cell Death; Cell Death; Cell Death by Oncosis (Oncotic Necrosis); Cell Membrane Injury Leading to Cell Death.; Free Radical Injury.; Morphologic Appearance of Necrotic Cells and Tissues (Oncotic Necrosis).; Gross Appearance of Necrotic Tissue.; Histologic Changes in Necrosis (Oncotic Necrosis).; Ultrastructure of Necrotic Cells (Oncotic Necrosis).; Types of Oncotic Necrosis.; Coagulative Necrosis.; Caseous Necrosis.; Liquefactive Necrosis.; Gangrenous Necrosis.; Necrosis of Epithelium. Necrosis of Adipose Tissue (Fat Necrosis). Sequelae to Oncotic Necrosis.; Morphologic Appearance of Postmortem Changes; Cell Death by Apoptosis; Triggers of Apoptosis.; The Extrinsic (Death Receptor-Initiated) Pathway.; The Intrinsic (Mitochondrial) Pathway.; The Execution Phase of Apoptosis.; Morphologic Appearance of Apoptosis.; Chronic Cell Injury and Cell Adaptations; Cellular Survival during Sublethal Ischemia or Involution; Autophagy; Adaptations That Change Cell Size, Number, or Appearance; Atrophy; Hypertrophy; Hyperplasia; Metaplasia; Dysplasia; Intracellular Accumulations; Lipids