Henry's clinical diagnosis and management by laboratory methods / edited by Richard A McPherson, MD, MSc, Professor Emeritus, Department of Pathology, Virginia Commonwealth University School of Medicine, Richmond, Virginia; Matthew R. Pincus, MD, PhD, Professor, Department of Pathology, SUNY Downstate Medical Center, Brooklyn, New York.

Includes bibliography and index

Part 1: The clinical laboratory. General concepts and administrative issues Optimizing laboratory workflow and performance Preanalysis Analysis: principles of instrumentation Mass spectrometry and applications Analysis: clinical laboratory automation Point-of-care testing and physician office laboratories Postanalysis: medical decision making Interpreting laboratory results Laboratory statistics Quality control Clinical laboratory informatics Financial management Ethics in laboratory medicine Part 2: Clinical chemistry. Evaluation of renal function, water , electrolytes and acid-base function Biochemical markers of bone metabolism Carbohydrates Lipids and dyslipoproteinemia Cardiac injury, atherosclerosis, and thrombotic disease Specific proteins Clinical enzymology Evaluation of liver function Laboratory diagnosis of gastrointestinal and pancreatic disorders Toxicology and therapeutic drug monitoring Evaluation of endocrine function Reproductive function and pregnancy Vitamins and trace elements Chemical basis for analyte assays and common interferences Part 3: Urine and other body fluids. Basic examination of urine Cerebrospinal, synovial, serous body fluids, and alternative specimens Part 4: Hematology and transfusion medicine. Basic examination of blood and bone marrow Hematopoiesis Erythrocytic disorders Leukocytic disorders The flow cytometric evaluation for hematopoietic neoplasia Immunohematology Transfusion medicine Hemapheresis Tissue banking and progenitor cells Part 5: Hemostasis and thrombosis. Coagulation and fibrinolysis Platelet disorders and von willebrand disease Laboratory approach to thrombotic risk Antithrombotic therapy Part 6: Immunology and immunopathology. Overview of the immune system and immunologic disorders Immunoassays and immunochemistry Laboratory evaluation of the cellular immune system Laboratory evaluation of immunoglobulin function and humoral immunity Mediators of inflammation: complement Mediators of inflammation: cytokines and adhesion molecules Human leukocyte antigen: the major histocompatibility complex of man The major histocompatibility complex and disease Immunodeficiency disorders Clinical and laboratory evaluation of systemic autoimmune rheumatic diseases Vasculitis Organ-specific autoimmune diseases Allergic diseases Part 7: Medical microbiology. Medical bacteriology In vitro testing of antimicrobial agents Mycobacteria Mycotic diseases Spirochete infections Chlamydial and mycoplasmal infections Rickettsiae and other related intracellular bacteria Viral infections Medical parasitology Specimen collection and handling for diagnosis of infectious diseases Part 8: Molecular pathology. Introduction to molecular pathology Molecular diagnostics: basic principles and techniques Polymerase chain reaction and other nucleic acid amplification technology Hybridization array technologies Applications of cytogenetics in modern pathology Molecular diagnosis of genetic diseases Molecular genetics of neuro-psychiatric disorders: current research and perspectives Identity testing: use of DNA analysis in parentage, forensic, and missing persons testing Pharmacogenomics and personalized medicine Part 9: Clinical pathology of cancer. Diagnosis and management of cancer using serologic and other body fluid markers Oncoproteins and early tumor detection Molecular diagnosis of hematopoietic neoplasms Molecular genetic pathology of solid tumors High-throughput genomic and proteomic technologies in the post-genomic era Appendices. Physiologic solutions, buffers, acid-base indicators, standard reference materials, and temperature conversions Desirable weights, body surface area, and body mass index Approximations of total blood volume Periodic table of elements SI units Common chimeric genes identified in human malignancies Disease/organ panels Guidelines for ordering blood for elective surgery

"This twenty-fourth edition marks more than 100 years since A Manual of Clinical Diagnosis, authored by James Campbell Todd, was introduced in 1908. In its current format as Henry's Clinical Diagnosis and Management by Laboratory Methods, this textbook remains the authoritative source of information for residents, students, and other trainees in the disciplines of clinical pathology and laboratory medicine, and for physicians and laboratory practitioners. The current edition continues the tradition of partnership between laboratory examinations and the formulation and confirmation of clinical diagnoses followed by monitoring of body functions, therapeutic drug levels, other results of medical treatments, and risk assessment for disease"--Publisher's description