Sirtuin biology in cancer and metabolic disease : cellular pathways for clinical discovery / edited by Kenneth Maiese.

Contributor(s):

Maiese, Kenneth [editor.]

Material type: Text

text

Media type:

unmediated

Carrier type:

volume

ISBN:

9780128224670

Subject(s):

LOC classification:

QP551 SIR

Contents:

Preface Section I: Sirtuins and metabolic disease 1. Sirtuins in metabolic disease: innovative therapeutic strategies with SIRT1, AMPK, mTOR, and nicotinamide Kenneth Maiese2. Sirtuins in metabolic and epigenetic regulation of stem cells Yi Fang and Xiaoling Li 3. Sirtuins and metabolic regulation: food and supplementation Sergio Henrique Sousa Santos, Victor Hugo Dantas Guimaraes, Janaina Ribeiro Oliveira, and Luiz Fernando Rezende 4. Sirtuins in diabetes mellitus and diabetic kidney disease Kultigin Turkmen 5. Sirtuins and mitochondrial dysfunction Jian-Li He, Tian-Shi Wang, and Yi-Ping Wang 6. Sirtuins in immunometabolism Hongxiu Yu 7. Mitochondrial sirtuins at the crossroads of energy metabolism and oncogenic transformation Maja Grabacka and Przemyslaw M. Plonka Section II: Sirtuins and cancer 8. Sirtuins and the hallmarks of cancerTalita H.B. Gomig, Tayana S. Jucoski, Erika P. Zambalde, Alexandre L.K. Azevedo, Daniela F. Gradia, and Enilze M.S.F. Ribeiro 9. The bifunctional roles of sirtuins and their therapeutic potential in cancer Yeuan Ting Lee, Yi Jer Tan, Pei Yi Mok, Ayappav. Subramaniam, and Chern Ein Oon 10. Sirtuins and next generation hallmarks of cancer: cellular energetics and tumor promoting inflammation Robert Kleszcz and Wanda Baer-Dubowska 11. Sirtuins and cellular metabolism in cancers Zhen Dong and Hongjuan Cui 12. Dual role of sirtuins in cancer Margalida Torrens-Mas and Pilar Roca 13. Sirtuin signaling in hematologic malignancies Ryan A. Denu 14. Impacts of sirtuin1 and sirtuin3 on oral carcinogenesis Shajedul Islam, Yoshihiro Abiko, Osamu Uehara, Yasuhiro Kuramitsu, and Itsuo Chiba Index

Summary: "Details the basic and clinical role of sirtuins and their broad applicability for sirtuin biology to be targeted for multiple medical disease entities Elucidates the research and advances on the biology of sirtuins, the application of these pathways upon cellular biology, and the translation of sirtuin pathways for the treatment of multiple disease entities Summarizes the multi-discipline views and publications for this diverse topic, covering cell development, cancer and metabolism"--

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Holdings
Item type	Current library	Call number	Copy number	Status	Date due	Barcode
Book	Medical School Open Shelf	QP551 SIR (Browse shelf(Opens below))	155308	Available		BK143001

Includes bibliography and references

"Details the basic and clinical role of sirtuins and their broad applicability for sirtuin biology to be targeted for multiple medical disease entities Elucidates the research and advances on the biology of sirtuins, the application of these pathways upon cellular biology, and the translation of sirtuin pathways for the treatment of multiple disease entities Summarizes the multi-discipline views and publications for this diverse topic, covering cell development, cancer and metabolism"--

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