Molecular diagnostics : fundamentals, methods, and clinical applications Lela Buckingham

Includes bibliographical references and index.

DNA -- RNA -- Protein -- Nucleic acid extraction methods -- Resolution and detection of nucleic acids -- Analysis and characterization of nucleic acids and proteins -- Nucleic acid amplification -- Chromosomal structure and chromosomal mutations -- Gene mutations -- DNA sequencing -- DNA polymorphisms and human identification -- Detection and identification of microorganisms -- Molecular detection of inherited diseases -- Molecular oncology -- DNA-based tissue typing -- Quality assurance and quality control in the molecular laboratory

This exceptional resource introduces the fundamentals of nucleic acid biochemistry as well as the advanced concepts integral to professional practice in today's laboratories. With a focus on the application of molecular concepts to diagnose diseases, the 2nd Edition reflects the many advances in this rapidly developing field.