Methods in enzymology: (Record no. 168630)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03859nam a22002897a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | ZW-GwMSU |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20241206083243.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 241206b |||||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780128053829 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | rda |
| Language of cataloging | English |
| Transcribing agency | MSULIB |
| Description conventions | rda |
| 050 ## - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QP601 RES |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Crowther R. A. |
| Relator term | editor |
| 245 10 - TITLE STATEMENT | |
| Title | Methods in enzymology: |
| Remainder of title | the resolution revolution : recent advances in cryoEM / |
| Statement of responsibility, etc | edited by R. A. Crowther. |
| 264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Name of producer, publisher, distributor, manufacturer | Elsevier/AP., |
| Date of production, publication, distribution, manufacture, or copyright notice | 2016. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | xx, 445 pages: |
| Other physical details | illustrations; |
| Dimensions | 25 cm |
| 336 ## - CONTENT TYPE | |
| Source | rdacontent |
| content type term | text |
| 337 ## - MEDIA TYPE | |
| source | rdamedia |
| media type term | unmediated |
| media type code | n |
| 338 ## - CARRIER TYPE | |
| source | rdacarrier |
| carrier type term | volume |
| carrier type code | nc |
| 490 ## - SERIES STATEMENT | |
| Series statement | Methods in enzymology, |
| Volume number/sequential designation | volume 579 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliography and index |
| 505 ## - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Front Cover; The Resolution Revolution: Recent Advances In cryoEM; Copyright; Contents; Contributors; Preface; References; Chapter One: Direct Electron Detectors; 1. Introduction; 2. Past; 3. Present; 3.1. Practical Advice for the User; 4. Future; References; Chapter Two: Specimen Behavior in the Electron Beam; 1. Introduction; 2. High-Energy Electrons Are a Form of Ionizing Radiation as Well as Being a Form of Short-Wavelength Radiation That Can B ... ; 2.1. Electron-Scattering Events Can Be Either Elastic or Inelastic. 2.2. Energy Is Deposited in the Specimen as a Result of Inelastic Scattering2.3. Values of the Linear Energy Transfer (LET) Can Be Used to Estimate the Energy Deposited; 3. Biological Molecules Become Structurally Damaged When Irradiated; 3.1. There Is a Large Literature of Radiation Chemistry and Radiation Biology; 3.2. Fading of Diffraction Patterns Is a Convenient Indicator of Structural Damage; 3.3. Some Residues in Proteins Are Especially Sensitive to Radiation Damage; 3.4. Caging of Fragments and ``Trapping ́́of Radicals Results in Cryo-Protection: This Helps Only to a Limited Extent. 3.5. Radiation Sensitivity of Enzyme Activity: Implications for Dynamic Studies in Liquid Samples4. Vitreous Ice Also Becomes Structurally Damaged by Ionizing Radiation; 4.1. Water Molecules Are Easily Damaged by Ionizing Radiation; 4.2. Weak Thon Rings at High Resolution Show That Vitreous Ice Is Very Sensitive to Radiation Damage; 4.3. Electron-Stimulated Desorption Progressively Thins Ice Specimens; 5. Bubbling of Hydrated Biological Specimens Becomes Apparent at High Electron Exposure; 5.1. Bubbles Consist of Molecular Hydrogen; 5.2. Bubbling Can Be Used to Evaluate the Specimen Thickness. 5.3. Bubbling Can Be Used to Distinguish Regions with Different Chemical Composition (Bubblegrams)6. Cryo-Specimens Exhibit Collective Beam-Induced Movement When Irradiated; 6.1. Radiation-Sensitive Specimens Show Beam-Induced Motion at Quite Low Electron Exposures; 6.2. Thin Cryo-Specimens Undergo Drum-Head-Like Flexing and Doming When Irradiated; 6.3. Images Can Be Corrupted Significantly by There Being Changes in Z-Height; 6.4. The Pattern of Beam-Induced Movement Can Be Quite Unpredictable; 7. More Than One Mechanism May Contribute to Beam-Induced Motion. 7.1. Cryo-EM Specimens, as Made, Are Expected to Be Under Considerable Stress7.2. Irradiation Can Relieve Mechanical Stress; 7.3. Irradiation Can Generate (New) Mechanical Stress; 7.4. Which Comes First, Relaxation or Creation of Stress?; 8. Irradiation Can Produce Electrostatic Charging of the Specimen; 8.1. A Buildup of Net Charge on the Specimen Can Be Easy to Detect; 8.2. Evidence of Net-Charge Buildup Can Be Reduced in Several Ways; 8.3. Other Forms of Specimen Charging Are More Subtle to Detect; 9. Summary and Future Directions; Acknowledgments; References |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cryoelectron |
| General subdivision | Microscopy |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cryomicroscopy |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pyle Anna Marie |
| Relator term | editor-in-Chief |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Christianson David W. |
| Relator term | editor-in-Chief |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Library of Congress Classification |
| Koha item type | Book |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Source of acquisition | Total Checkouts | Full call number | Barcode | Date last seen | Copy number | Cost, replacement price | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Library of Congress Classification | Medical School | Medical School | Open Shelf | 06/12/2024 | Book Aid International | QP601 MET | BK151888 | 06/12/2024 | 163762 | 199.00 | 06/12/2024 | Book |