Drug discovery in cancer epigenetics (Record no. 155319)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02142nam a22003137a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | ZW-GwMSU |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20201012153942.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201012b ||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780128022085 |
| 040 ## - CATALOGING SOURCE | |
| Language of cataloging | English |
| Transcribing agency | MSU |
| Description conventions | rda |
| 245 ## - TITLE STATEMENT | |
| Title | Drug discovery in cancer epigenetics |
| Statement of responsibility, etc | edited by Gerda Egger and Paola Arimondo |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc | Oxford : |
| Name of publisher, distributor, etc | Elsevier, |
| Date of publication, distribution, etc | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 475 pages : |
| Other physical details | ill(chiefly color) |
| Dimensions | 25 cm |
| 336 ## - CONTENT TYPE | |
| Source | rdacontent |
| content type term | text |
| 337 ## - MEDIA TYPE | |
| source | rdamedia |
| media type term | unmediated |
| media type code | n |
| 338 ## - CARRIER TYPE | |
| source | rdacarrier |
| carrier type term | volume |
| carrier type code | nc |
| 490 ## - SERIES STATEMENT | |
| Series statement | Translational epigenetics series |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references and index |
| 505 ## - FORMATTED CONTENTS NOTE | |
| Formatted contents note | I. Introduction. Basic epigenetic mechanisms and phenomena -- Cancer epigenetics -- II. Methods and tools for epigenetic drug development -- Drug discovery methods -- Preclinical cancer models with the potential to predict clinical response -- Discovery of biomarkers for drug development -- Networks and consortia for epigenetic drug discovery -- III. Classes of epigenetic drugs -- DNA methyltransferase inhibitors -- Small molecule inhibitors of histone deacetylases and acetyltransferases as potential therapeutics in oncology -- Targeting histone methylation. The development of selective methyltransferase and demethylase inhibitors -- Bromodomains as anti-cancer targets -- Epigenetic readers interpreting the lysine methylome: biological roles and drug discovery -- Non coding RNAs: clinical and therapeutic applications -- IV. Clinical implications of epigenetic therapy. Clinical applications of epigenetic drugs -- Efficacy of combined epigenetic therapies -- Predicting and monitoring responses to epigenetic drugs -- Episensitization: a new word for a new concept -- The emerging potential for epigenetic therapeutics in non-cancer disorders |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cancer |
| General subdivision | Genetic aspects |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Epigenetics |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neoplasms |
| General subdivision | drug therapy |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Gene expression |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug development |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neoplasms |
| General subdivision | genetics |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Egger, Gerda |
| Relator term | editor |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Arimondo, Paola |
| Relator term | editor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Library of Congress Classification |
| Koha item type | Book |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Source of acquisition | Cost, normal purchase price | Full call number | Barcode | Date last seen | Copy number | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Library of Congress Classification | Medical School | Medical School | Open Shelf | 12/10/2020 | Book Aid | 90.00 | RC268.4 DRU | BK138374 | 12/10/2020 | 150701 | 12/10/2020 | Book |