MARC details
| 000 -LEADER |
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| fixed length control field |
03560nam a22003377a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
ZW-GwMSU |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20200701092109.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
200608b ||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781907568176 (hbk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
1907568174 (hbk.) |
| 040 ## - CATALOGING SOURCE |
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| Language of cataloging |
English |
| Transcribing agency |
MSU |
| Description conventions |
rda |
| 041 ## - |
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| -- |
eng |
| 050 ## - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QP134047 |
| 245 00 - TITLE STATEMENT |
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| Title |
Protein folding in silico : |
| Remainder of title |
protein folding versus protein structure prediction |
| Statement of responsibility, etc |
edited by Irena Roterman-Konieczna |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Place of publication, distribution, etc |
Oxford |
| Name of publisher, distributor, etc |
Woodhead Publishing |
| Date of publication, distribution, etc |
2012 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
208 pages |
| Other physical details |
coloured illustrations |
| Dimensions |
24 cm |
| 336 ## - CONTENT TYPE |
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| Source |
rdacontent |
| content type term |
text |
| 337 ## - MEDIA TYPE |
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| source |
rdamedia |
| media type term |
unmediated |
| media type code |
n |
| 338 ## - CARRIER TYPE |
|---|
| source |
rdacarrier |
| carrier type term |
volume |
| carrier type code |
nc |
| 490 1# - SERIES STATEMENT |
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| Series statement |
Woodhead publishing series in biomedicine |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc |
Includes bibliographical references and index. |
| 505 ## - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Dedication List of figures List of tables About the editor List of contributors Introduction Chapter 1: The early-stage intermediate Abstract 1.1 Geometric model 1.2 Structural alphabet 1.3 Contingency table 1.4 In search of structural similarities Chapter 2: The late-stage intermediate Abstract: 2.1 The " fuzzy oil drop " model 2.2 Quantitative description of the hydrophobic core 2.3 Protein characteristics with respect to the hydrophobic core 2.4 Simulation of late-stage folding Chapter 3: Structural information involved in the interpretation of the stepwise protein folding process Abstract: 3.1 Balancing the quantity of information in the amino acid sequence and the early-stage intermediate 3.2 Zones on the Ramachandran map Chapter 4: The divergence entropy characterizing the internal force field in proteins Abstract: 4.1 Internal force field for nonbonding interactions 4.2 The impact of ligands 4.3 Structures of homodimers - protein-protein interaction 4.4 Protein containing a catalytic center 4.5 The role of exons 4.6 Conclusions Chapter 5: Ligand-binding-site recognition Abstract: 5.1 General model 5.2 ROC curves 5.3 Summary Chapter 6: Use of the aEUROoefuzzy oil dropaEURO model to identify the complexation area in protein homodimers Abstract: 6.1 General description 6.2 ROC curves 6.3 Conclusions Chapter 7: Simulation of the polypeptide chain folding process using the "fuzzy oil drop" model Abstract: 7.1 Simulation of the folding process in the presence of an external hydrophobic force field 7.2 Folding in the presence of a ligand 7.3 Influence of external factors on polypeptide chain folding Chapter 8: Misfolded proteins Abstract: 8.1 Introduction 8.2 In silico experiment 8.3 Conclusions 8.4 Appendix 1: details of the molecular dynamics simulation 8.5 Appendix 2: details of the cluster analysis Chapter 9: A Short description of other selected ab initio methods for protein structure prediction Abstract: 9.1 Introduction 9.2 Simplifying the geometric model and the field function 9.3 Lattice model 9.4 ROSETTA 9.5 In search of a global minimum - force field deformation Chapter 10: Conclusion Abstract: 10.1 Acknowledgements Index |
| 520 8# - SUMMARY, ETC. |
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| Summary, etc |
Protein folding in silico is broad in scope - starting with ab initio models and attempting to construct a mechanistic model on the basis of their predictions. The authors' computational model is expected to go beyond experimental studies, casting a new light on the complexities of biological phenomena -- |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Protein folding |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Protein folding |
| General subdivision |
Simulation methods |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Protein folding |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Computer simulation |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Models, Theoretical |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Roterman-Konieczna, Irena |
| Relator term |
Editor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Library of Congress Classification |
| Koha item type |
Book |