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Radical scavenging efficacy of Thiol capped silver nanoparticles

Chandraker, Kumudini

Radical scavenging efficacy of Thiol capped silver nanoparticles Kumudini Chandraker, Sandeep Kumar Vaishanav, Rekha Nagwanshi and Manmohan L Satnami - Journal of chemical sciences Volume 127, number 12, .

Radical scavenging efficacy of L-cysteine (L-Cys), glutathione (GSH) and thioctic acid (TA) in the presence of silver nanoparticles (AgNPs) were determined by 1,1-diphenyl 2-picryl hydrazil (DPPH), nitric oxide (NO) and hydroxyl (OH) radicals as spectrophotometric assay. The hydrogen peroxide (H 2 O 2) scavenging efficacy has been determined by titration method. Ascorbic acid has been used as standard for all radical scavenging efficacies. In general, antioxidant activity decreases in the presence of AgNPs. The covalent interactions of thiols (-SH) were found to be a key factor for the decreases in scavenging activity. The effect of thiol concentrations has been discussed. The size and shape of the nanoparticles and AgNP-SR interactions have been characterized through Transmission Electron Microscopy (TEM) and Fourier Transform Infrared (FTIR) spectroscopy, respectively.

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Silver nanoparticle--Thiol--Radical scavenging efficacy

QD31 JOU