Midlands State University Library

Nano-TiCl4/SiO2 : an efficient heterogeneous solid acid catalyst for the one pot cascade five-component synthesis of densely functionalized tetrahydropyridines /

Bamoniri, A.

Nano-TiCl4/SiO2 : an efficient heterogeneous solid acid catalyst for the one pot cascade five-component synthesis of densely functionalized tetrahydropyridines / created by A. Bamoniri, B. Mirjalili and Reza Tarazian - Journal of chemical sciences Volume 127, number 5, .

Nano-TiCl4/SiO2 was found to be an inexpensive and efficient heterogeneous solid acid catalyst for the synthesis of one-pot cascade synthesis of highly functionalized asymmetric tetrahydropyridines from the five-component condensation reaction of the para-substituted anilines and aromatic aldehydes with ethyl acetoacetate under thermal conditions. Novel methodology, environmentally benign conditions, clean protocol, easy work-up and high yields are the important advantages of this protocol. The products were characterized using physical and spectroscopic data such as FT-IR, 1H-NMR and in some cases 13C-NMR and CHN analysis.

09743626


Tetrahydropyridines--Heterogeneous catalyst--Nano-TiCl4/SiO2

QD31 JOU